Hope's Peak Academy is a special school, recognized by the government, that was established in order to gather and nurture top-class students who excel in various fields. This school has two courses: The main course, and the preparatory course. Anyone with the money can enter the preparatory course, even if they don't have any special skills. The 77th class of the main course is filled with students who not only have unique abilities, but unique personalities as well. However, the students learned that "Talent isn't the most important thing in life; it's to involve yourself with people and make yourself a better person while making memories." However, little did they know that a mysterious project and discrimination of the courses were happening right under their noses. Hajime Hinata, a boy from the preparatory class who craves for an ability. The fateful meeting he has drives the future of the school into an unimaginable direction. This is the story of what happened up until the "The Biggest, Most Awful, Most Tragic Event in Human History." This is a story of hope that ends in despair.